Canon, Non-Canon, Yaoi, Yuri - whatever floats your boat, list them here!
Fakir x Duck from Princess Tutu
This pairing gives me the warm fuzzies and I don't know why. Side note: my little sisters couldn't stop giggling when somebody said Fakir's name in the show.
Tsukasa x Subaru from .Hack//Sign
I like this couple since they looked out for each other throughout the show and I found that very endearing..
Tanda x Balsa from Moribito: Guardian of the Spirit
One, I have a thing for 'older' couples. They're past the dumb teenage puppy love and in that way it seems more geniune. Two, this one is funny since the guy acts like the wife and the girl, the husband. Poor Tanda..
Tai x Sora from Digimon Adventure
@$&#$&#*$& ZERO TWO EPILOGUE. RAAAAAAGE. >:0
Hiei x Kurama from Yu Yu Hakusho
*oogles* 0-0 The image below the cut is an official artwork. I am not totally making this up..
Yusuke x Keiko from Yu Yu Hakusho
Love interests for the shounen hero are a dime a dozen but how many actually end up working in the end?
Kuranosoke x Tsukimi from Princess Jellyfish
Nerdy girl meets crossdressing guy. (Hint: the guy is on the right :3)
Hige x Blue from Wolf's Rain
;_;
Hubb x Cher from Wolf's Rain
Again, older couples. Love'em
Isaac x Mira from Baccano!
These two were made for each other. They're complete and utter idiots

Ok. I should stop for now before this post gets even longer.